Search results for " nylon"

showing 3 items of 3 documents

Human Topoisomerase I interaction with DNA on flexible nylon substrate for malaria diagnosis

The study of interaction between human Topoisomerase I (hTopo I) and the appropriate sequences of DNA is shown, with the aim to realize a biosensor for malaria diagnosis. Topoisomerases alter the topological state of DNA by catalysing the breaking and rejoining of DNA strands1. The ligase activity is fundamental for our biosensing strategy, revealing the pathology. hTopo I was chosen as a model system for the Plasmodium analogous. The biosensor is a new flexible and easy to degrade biochip printed on nylon by dip-pen lithography (DPL). It is realized exploiting the high specificity of complementary ssDNA2 and hTopo I ligase activity. DPL operation needs ultra-low amounts of DNA (0.5 µL) to …

topoisomerase biosensor nylon dip-pen lithography fluorescenceSettore CHIM/02 - Chimica Fisica
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Imbibition of Femtoliter-Scale DNA-Rich Aqueous Droplets into Porous Nylon Substrates by Molecular Printing

2019

This work presents the first reported imbibition mechanism of femtoliter (fL)-scale droplets produced by microchannel cantilever spotting (μCS) of DNA molecular inks into porous substrates (hydrophilic nylon). Differently from macroscopic or picoliter droplets, the downscaling to the fL-size leads to an imbibition process controlled by the subtle interplay of evaporation, spreading, viscosity, and capillarity, with gravitational forces being quasi-negligible. In particular, the minimization of droplet evaporation, surface tension, and viscosity allows for a reproducible droplet imbibition process. The dwell time on the nylon surface permits further tuning of the droplet lateral size, in acc…

Materials scienceDiffusionSettore CHIM/05 - Scienza e Tecnologia dei Materiali PolimericiEvaporation02 engineering and technology010402 general chemistry01 natural sciencesSurface tensionMolecular ImprintingViscosityElectrochemistrySurface TensionGeneral Materials Sciencedroplets imbibition molecular printing nylon substrates biosensors microarraysPorositySpectroscopyMicrochannelFemtoliterNucleic Acid HybridizationWaterSurfaces and InterfacesDNA021001 nanoscience & nanotechnologyCondensed Matter Physics0104 chemical sciencesNylonsChemical engineeringSettore CHIM/03 - Chimica Generale E InorganicaImbibition0210 nano-technologyHydrophobic and Hydrophilic InteractionsPorosity
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Termo- e foto- degradazione di nano compositi a base di nylon 11

2016

Negli ultimi anni la poliammide 11 (PA11) ha suscitato un notevole interesse in svariati settori industriali industriali.Per ottimizzare la comprensione dei meccanismi che governano la termo e foto ossidazione della PA11, sono stati studiati mediante Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF-MS) , cromatografia ad esclusione sterica (SEC) e viscosimetria, i processi di degradazione termo e foto-ossidativi che interessano il PA11 ed in particolare i nanocompositi formulati con Cloisite30B

Termo-ossidazione foto-degradazione nanocompositi nylon 11
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